Angelo Stano was born in Bari in 1953, and dropped out of University in 1971 to devote himself to a career in graphics. Two years later, he published his first work for the comics magazine L'Avventuroso. During the 70s, his work appeared in collections like 'Uomini e Guerra' by Dardo and in the magazine Corrier-Boy. He collaborated with Pino Dangelico on series like 'Terror' and 'Oltretomba', and worked on 'Charlie Charleston' in 1977.
In 1982, Angelo Stano started drawing for the Bonelli series 'Martin Mystère', originally created by Alfredo Castelli and Giancarlo Alessandrini. He was also original artist of 'Dylan Dog' (1986), the bestseller series created by Tiziano Sclavi, and is still active as the series' cover artist.